Brazilian midfielder Paulinho has been ruled out of action until February and he joins Jan Vertonghen, Younes Kaboul, Sandro and Andros Townsend on the Tottenham treatment table.
Sherwood will also have Kyle Walker available again after he missed the last game through suspension.
Man Utd News
David Moyes is sweating on the fitness of Wayne Rooney with United’s key man missing the win over Norwich. He has a chance of being passed fit, but will undergo late checks.
Robin van Persie is not expected to be fit enough to start the game for the visit of Tottenham, but could well make an appearance on the bench.
Antonio Valencia is free again from suspension, but Phil Jones, Rafael and Marouane Fellaini are all long-term concerns.